直播預告|江小寧教授講述精準生物醫學超聲

直播時間：2024年3月29日（周五）20:00-21:30

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北京時間2024年3月29日晚八點，iCANX Talks 第179期邀請到了北卡羅來納州立大學Xiaoning Jiang教授進行分享！此外，北京航空航天大學Jianguo Ma，仁荷大學Howuk Kim，北京大學Mengdi Han三位教授擔任嘉賓，北京大學Ji Wan博士作為挑戰者，北京大學Haixia Zhang教授擔任主持人。

【嘉賓介紹】

Xiaoning Jiang

北卡羅來納州立大學

Toward Precision Biomedical Ultrasound

【Abstract】

In recent years, there has been a remarkable advancement in biomedical ultrasound technology, particularly in the field of miniaturized transducers. These innovations have paved the way for precise and minimally invasive diagnosis and treatment of increasingly concerned diseases such as cardiovascular disease (CVD) and cancer. In this talk, micro/nanotechnology enabled small aperture ultrasound transducers were designed, fabricated and tested for precision biomedical ultrasound imaging, therapy and drug delivery. In specific, we investigated high frequency transducers for advanced intravascular ultrasound (IVUS) imaging. Small aperture forward-looking and vortex transducers were successfully demonstrated in-vitro for effective microbubbles and nanodroplets mediated intravenous sonothrombolysis. Moreover, miniaturized transducers enabled sonoporation was successful in enhancing localized drug delivery. These new findings suggest that precision biomedical ultrasound via minimal invasion can be significant in advanced ultrasound imaging, therapy, and drug delivery for unprecedented disease diagnosis and treatment.

近年來，生物醫學超聲技術取得了顯著的進步，特別是在小型化換能器領域。這些創新為心血管疾病（CVD）和癌癥等日益受到關注的疾病的精確和微創診斷和治療鋪平了道路。在本次演講中，我將報告用于精密生物醫學超聲成像、治療和藥物輸送，基于微/納米技術的小孔徑超聲換能器的設計、制造和測試。具體來說，我們研究了用于先進血管內超聲 (IVUS) 成像的高頻換能器。小孔徑前視和渦流換能器已在體外成功證明可用于有效的微泡和納米液滴介導的靜脈超聲溶栓。此外，微小型換能器實現的聲孔作用可以顯著增強局部藥物輸送。這些新發現表明，通過微創實現的精準生物醫學超聲在先進超聲成像、治療和藥物輸送方面具有重要意義，可幫助實現前所未有的疾病診斷和治療。

【BIOGRAPHY】

Xiaoning Jiang is the Dean F. Duncan Distinguished Professor of Mechanical and Aerospace Engineering and a University Faculty Scholar at North Carolina State University. He is also an Adjunct Professor of Biomedical Engineering at North Carolina State University and University of North Carolina, Chapel Hill, and an Adjunct Professor of Neurology in Duke University. Dr. Jiang received his Ph.D. degree from Tsinghua University (1997) and his Postdoctoral training from the Nanyang Technological University (1996-1997) and the Pennsylvania State University (1997-2001). He was the Chief Scientist and Vice President for TRS Technologies, Inc. prior to joining NC State in 2009. Dr. Jiang is the author and co-author of two books, 6 book chapters, 11 issued US Patents, more than 180 peer reviewed journal papers and over 140 conference papers on piezoelectric ultrasound transducers, ultrasound for medical imaging and therapy, drug delivery, ultrasound NDT/NDE, smart materials and structures and M/NEMS. Dr. Jiang served as the Vice President for Technical Activities in IEEE Nanotechnology Council (NTC) (2022-2023). He was the Co-Editor-in-Chief of IEEE Nanotechnology Magazine (2020 - 2021) and an IEEE NTC Distinguished Lecturer in 2018-2019. Dr. Jiang is an ASME Fellow, a SPIE Fellow and an IEEE Fellow.

江小寧是北卡羅來納州立大學機械與航空航天工程系 Dean F. Duncan 杰出教授、大學教員學者。他還是北卡羅來納州立大學和北卡羅來納大學教堂山分校的生物醫學工程兼職教授，以及杜克大學神經病學兼職教授。江博士于1997年獲得清華大學博士學位，在南洋理工大學（1996-1997）和賓夕法尼亞州立大學（1997-2001）進行博士后研究。在 2009 年加入北卡羅來納州立大學之前，他曾擔任 TRS Technologies, Inc. 的首席科學家兼副總裁。江博士與合作者發表了有關壓電超聲換能器、超聲醫學成像和治療、藥物輸送、超聲 無損檢測、智能材料和結構以及 M/NEMS的書籍（2）、書籍章節（6），11 項美國專利、180 多項同行評審期刊文章和140 多篇會議論文。江博士曾擔任 IEEE 納米技術委員會（NTC）技術活動副總裁（2022-2023）。他曾擔任 IEEE 納米技術雜志聯合主編（2020-2021 年），并于 2018-2019 年擔任 IEEE NTC 杰出講師。