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    發布時間:2022-08-05 15:22 原文鏈接: 與膽管癌相關的MAGEH1基因編碼功能描述

    該基因屬于黑色素瘤相關抗原(MAGE)超家族的非CT(非癌癥/睪丸)亞群。編碼蛋白可能與細胞凋亡、細胞周期停滯、生長抑制或細胞分化有關。該蛋白可能通過STAT1α(信號轉導子和轉錄激活子1α)途徑參與ATRA(全反式維甲酸)信號傳導。
    This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway.

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