核糖體是催化蛋白質合成的細胞器，由一個小的40S亞單位和一個大的60S亞單位組成。這些亞單位由4種RNA和大約80種結構不同的蛋白質組成。這個基因編碼一種細胞質核糖體蛋白，它是40S亞單位的組成部分。該蛋白屬于核糖體蛋白的S6E家族。是核糖體中蛋白激酶的主要底物，五個C端絲氨酸殘基的亞群被不同的蛋白激酶磷酸化。磷酸化是由多種刺激物誘導的，包括生長因子、腫瘤促進劑和有絲分裂原。生長停滯時發生去磷酸化。該蛋白可通過選擇性翻譯特定類別的mRNA來幫助控制細胞的生長和增殖。與編碼核糖體蛋白的基因一樣，該基因有多個經過處理的假基因散布在基因組中。
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.