該基因是小GTP酶超家族的成員,編碼一種脂質錨定的細胞膜蛋白,具有5個重復的ras相關GTP結合區。由于這種蛋白在胰島素/Tor/S6K信號通路中的作用,它在調節生長和細胞周期進程中是至關重要的。蛋白質具有GTP酶活性,在GDP結合形式和GTP結合形式之間穿梭,這種活性需要蛋白質的法呢酰化。已經繪制了三個假基因,其中兩個在10號染色體上,另一個在22號染色體上。 This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.