• <option id="immmk"></option>
  • <noscript id="immmk"><kbd id="immmk"></kbd></noscript>
    發布時間:2022-08-05 09:37 原文鏈接: 與肺癌相關的PBK基因編碼功能描述

    該基因編碼一種絲氨酸/蘇氨酸蛋白激酶,與雙特異性絲裂原活化蛋白激酶(MAPKK)家族有關。有證據表明,有絲分裂磷酸化是必需的催化活性。編碼蛋白可能參與淋巴細胞的激活和支持睪丸功能,并在精子發生過程中發揮作用。這種基因的過度表達與腫瘤發生有關。選擇性剪接導致多個轉錄變體。
    This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.

  • <option id="immmk"></option>
  • <noscript id="immmk"><kbd id="immmk"></kbd></noscript>
    伊人久久大香线蕉综合影院首页